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Normative Data for Cortical Evoked Response Audiometry of a Heterogeneous Indian Population and Its Comparison with Behavioral Audiometry.
Annals of Indian Academy of Neurology ( IF 1.9 ) Pub Date : 2020-05-01 , DOI: 10.4103/aian.aian_397_18 Priyanka Misale 1 , Anjali Lepcha 1 , Philip Thomas 2 , Swapna Sebastian 2 , Tunny Sebastian 3
Objective: The objective of the study is to establish normative values of cortical evoked response audiometry (CERA) in a heterogeneous Indian population and correlate CERA threshold with pure tone audiometric (PTA) threshold values. Materials and Methods: A prospective study was carried out on 31 volunteers (n = 62) who had no otological or neurological complaints. Two study groups were formed; Group 1 with individuals from 20 to 40 years (mean age of 29.1 years) and Group 2 with individuals from 41 to 60 years (mean age of 46.2 years). The latencies and amplitudes of the waves of P1, N1, and P2 at threshold and 70 dBnHL were measured. Results: Twenty-nine participants (94% of the ears) had CERA threshold within 20 dB of true behavioral threshold with only 6% having a difference of >20 dB with their PTA thresholds. There was a significant difference (P < 0.05) at 70 dB in amplitudes for waves P1, N1, and P2 at 2 kHz and additionally at 1 kHz for N1 between the two groups. Conclusion: Normative values for CERA in a heterogeneous Indian population at 70 dB nHL using tone burst stimulus was found to have an average latency of 46.5, 90.1, and 155.5 ms for P1, N1, and P2, respectively. The average amplitude of P1 at 70 dB nHL was 4.3 μV, N1, was 6.5 μV and P2 was 3.2 μV. Hearing threshold obtained with CERA gave a good indication of the actual behavioral hearing threshold of the normal controls, and the age of an individual had a significant effect on the values obtained during CERA testing with N1 being significantly larger at 1 kHz and 2 kHz in older adults when compared to young adults.
中文翻译：
异质印度人口皮层诱发反应测听的规范数据及其与行为测听的比较。
目的：本研究的目的是在异质的印度人群中建立皮质诱发反应测听 (CERA) 的规范值，并将 CERA 阈值与纯音测听 (PTA) 阈值相关联。材料和方法：对没有耳科或神经系统疾病的 31 名志愿者（ n = 62）进行了一项前瞻性研究。成立了两个研究小组；第 1 组的个体为 20 至 40 岁（平均年龄为 29.1 岁），第 2 组的个体为 41 至 60 岁（平均年龄为 46.2 岁）。测量了阈值和 70 dBnHL 处 P1、N1 和 P2 波的延迟和幅度。结果：29 名参与者（94% 的耳朵）的 CERA 阈值在真实行为阈值的 20 dB 范围内，只有 6% 的参与者与其 PTA 阈值的差异 > 20 dB。两组之间在 70 dB 处波 P1、N1 和 P2 在 2 kHz 和另外在 1 kHz 处 N1 的幅度有显着差异 ( P < 0.05)。结论：发现在 70 dB nHL 下使用音调脉冲刺激的异质印度人群中 CERA 的规范值对于 P1、N1 和 P2 的平均潜伏期分别为 46.5、90.1 和 155.5 ms。P1 在 70 dB nHL 时的平均幅度为 4.3 μV，N1 为 6.5 μV，P2 为 3.2 μV。用 CERA 获得的听力阈值很好地表明了正常对照组的实际行为听力阈值，并且个体的年龄对 CERA 测试期间获得的值有显着影响，在 1 kHz 和 2 kHz 时 N1 显着更大与年轻人相比，成年人。
更新日期：2020-05-01
Annals of Indian Academy of Neurology ( IF 1.9 ) Pub Date : 2020-05-01 , DOI: 10.4103/aian.aian_397_18 Priyanka Misale 1 , Anjali Lepcha 1 , Philip Thomas 2 , Swapna Sebastian 2 , Tunny Sebastian 3
Affiliation
Objective: The objective of the study is to establish normative values of cortical evoked response audiometry (CERA) in a heterogeneous Indian population and correlate CERA threshold with pure tone audiometric (PTA) threshold values. Materials and Methods: A prospective study was carried out on 31 volunteers (n = 62) who had no otological or neurological complaints. Two study groups were formed; Group 1 with individuals from 20 to 40 years (mean age of 29.1 years) and Group 2 with individuals from 41 to 60 years (mean age of 46.2 years). The latencies and amplitudes of the waves of P1, N1, and P2 at threshold and 70 dBnHL were measured. Results: Twenty-nine participants (94% of the ears) had CERA threshold within 20 dB of true behavioral threshold with only 6% having a difference of >20 dB with their PTA thresholds. There was a significant difference (P < 0.05) at 70 dB in amplitudes for waves P1, N1, and P2 at 2 kHz and additionally at 1 kHz for N1 between the two groups. Conclusion: Normative values for CERA in a heterogeneous Indian population at 70 dB nHL using tone burst stimulus was found to have an average latency of 46.5, 90.1, and 155.5 ms for P1, N1, and P2, respectively. The average amplitude of P1 at 70 dB nHL was 4.3 μV, N1, was 6.5 μV and P2 was 3.2 μV. Hearing threshold obtained with CERA gave a good indication of the actual behavioral hearing threshold of the normal controls, and the age of an individual had a significant effect on the values obtained during CERA testing with N1 being significantly larger at 1 kHz and 2 kHz in older adults when compared to young adults.
中文翻译：
异质印度人口皮层诱发反应测听的规范数据及其与行为测听的比较。
目的：本研究的目的是在异质的印度人群中建立皮质诱发反应测听 (CERA) 的规范值，并将 CERA 阈值与纯音测听 (PTA) 阈值相关联。材料和方法：对没有耳科或神经系统疾病的 31 名志愿者（ n = 62）进行了一项前瞻性研究。成立了两个研究小组；第 1 组的个体为 20 至 40 岁（平均年龄为 29.1 岁），第 2 组的个体为 41 至 60 岁（平均年龄为 46.2 岁）。测量了阈值和 70 dBnHL 处 P1、N1 和 P2 波的延迟和幅度。结果：29 名参与者（94% 的耳朵）的 CERA 阈值在真实行为阈值的 20 dB 范围内，只有 6% 的参与者与其 PTA 阈值的差异 > 20 dB。两组之间在 70 dB 处波 P1、N1 和 P2 在 2 kHz 和另外在 1 kHz 处 N1 的幅度有显着差异 ( P < 0.05)。结论：发现在 70 dB nHL 下使用音调脉冲刺激的异质印度人群中 CERA 的规范值对于 P1、N1 和 P2 的平均潜伏期分别为 46.5、90.1 和 155.5 ms。P1 在 70 dB nHL 时的平均幅度为 4.3 μV，N1 为 6.5 μV，P2 为 3.2 μV。用 CERA 获得的听力阈值很好地表明了正常对照组的实际行为听力阈值，并且个体的年龄对 CERA 测试期间获得的值有显着影响，在 1 kHz 和 2 kHz 时 N1 显着更大与年轻人相比，成年人。
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