The motivation behind this article is to give point‐by‐point data about the beneficial applications of oregano feed supplement in fish diets as immunomodulators, antioxidant, antiviral, antifungal and antiparasitic. Use of this plant as feed additive plays an important role in the fish diet when compared to other synthetic feed additives. Oregano is rich in phytochemical compounds including carvacrol and thymol in addition to other phenolic compounds with antioxidant and immune‐enhancing activities. Origanum vulgare extract improved the immunological responses and enhanced non‐specific immunity. Also, non‐specific immunity and the lysosomal activity were significantly increased in rainbow trout fed diet enriched with 3.0 mL essential oil of Origanum onites L kg⁻¹ diet for 60 days. Furthermore, non‐specific immune stimulant, antioxidant and nitric oxide activities were improved due to O. vulgare oil supplementation. In some recent studies, Origanum heracleoticum L essential oil as a growth enhancer increased the antioxidant status. In rainbow trout, the hepatic levels of antioxidant enzymes and the total antioxidant capacity increased by feeding diet enriched with 6 and 10 g kg⁻¹ diet of O. vulgare extract. Therefore, the addition of oregano and/or derivatives as a dietary supplement in fish diet may promote growth and enhance the immunity and health of fish and this will be useful for nutritionists, physiologists and veterinarians.

中文翻译：

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牛至草及其衍生物作为鱼类免疫调节剂的作用

本文的目的是逐点给出有关牛至饲料补充剂在鱼类日粮中作为免疫调节剂，抗氧化剂，抗病毒剂，抗真菌剂和抗寄生虫剂的有益应用的逐点数据。与其他合成饲料添加剂相比，使用这种植物作为饲料添加剂在鱼类饮食中起着重要作用。牛至含有丰富的植物化学化合物，包括香芹酚和百里香酚，以及其他具有抗氧化和增强免疫活性的酚类化合物。牛至提取物改善了免疫反应并增强了非特异性免疫。此外，富含3.0 mL牛至油L kg ^-1的牛至精油的虹鳟鱼日粮中非特异性免疫力和溶酶体活性也显着提高。饮食60天。此外，由于添加了普通粗麦油，非特异性免疫刺激剂，抗氧化剂和一氧化氮活性得到改善。在最近的一些研究中，牛至精油L作为生长促进剂可以增加抗氧化剂的状态。在虹鳟鱼中，通过饲喂富含6和10 g kg - ¹日粮的普通大麦提取物的饮食，肝脏的抗氧化酶水平和总抗氧化能力增加。因此，在鱼饲料中添加牛至和/或衍生物作为膳食补充剂可促进鱼的生长并增强鱼的免疫力和健康，这对于营养学家，生理学家和兽医将是有用的。