Few interactions between risk factors for schizophrenia have been replicated, but fitting all such interactions is difficult due to high‐dimensionality. Our aims are to examine significant main and interaction effects for schizophrenia and the performance of our approach using simulated data.

中文翻译：

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风险因素及其相互作用的稳健数据驱动识别：对精神分裂症父母和人口统计学风险因素的模拟和研究。

精神分裂症风险因素之间的相互作用很少被复制，但由于高维，很难拟合所有这些相互作用。我们的目标是使用模拟数据检查精神分裂症的显着主要效应和相互作用效应以及我们方法的性能。