Achievement of adequate implant stability is one of the determinants for long-term successful osseointegration. Resonance frequency analysis was developed to monitor implant stability and is now a well-recognized, non-invasive tool for determining the appropriate time for functional loading. However, there have been few studies with continuous evaluation and comparison of implant stability and marginal bone level changes between two different macro designs and clinical situations during the implant healing process. Thus, the purpose of this clinical trial is to evaluate the implant stability and marginal bone level changes of straight and conical implants during the implant healing process.

In this prospective clinical trial, 25 participants were randomized to either straight or conical implants. A total of 32 titanium dental implants with a length of 9 mm or 11 mm were installed in the maxilla and the mandible according to the manufacturer’s instructions. A resonance frequency analyzer was used to measure the implant stability quotient (ISQ) at the time of implant placement and after 2 weeks, 4 weeks, 6 weeks, 8 weeks, 10 weeks, and 12 weeks of healing. The changes in the peri-implant marginal bone level were evaluated from digital radiographic films taken at the time of implant placement and after 4 weeks, 8 weeks, and 12 weeks of healing. The preliminary results of this study revealed higher ISQ values and better healing tendency for conical implants in comparison with straight implants in the maxilla. Similar ISQ values and healing tendency were observed for straight and conical implants in the mandible. No significant differences in marginal bone loss were found between the straight and conical implants. However, in the mandible, slightly more marginal bone loss was found with the conical implants than straight implants after 12 weeks of healing.

In conclusion, ISQ healing tendency and marginal bone loss are influenced by implant macro-design and jaw regions. Straight implants revealed similar ISQ healing tendency and marginal bone loss in both the mandible and maxilla. Conical implants were confirmed more beneficial for maintenance of implant stability and marginal bone level in the maxilla.

获得足够的植入物稳定性是长期成功完成骨整合的决定因素之一。共振频率分析用于监测植入物的稳定性，现在已成为公认的非侵入性工具，用于确定适当的功能加载时间。但是，很少有研究能够对植入物愈合过程中两种不同的宏观设计和临床情况之间的植入物稳定性和边缘骨水平变化进行连续评估和比较。因此，该临床试验的目的是评估植入物愈合过程中笔直和圆锥形植入物的植入物稳定性和边缘骨水平变化。

在这项前瞻性临床试验中，将25名参与者随机分为直形或圆锥形植入物。根据制造商的说明，在上颌骨和下颌骨中总共安装了32颗9毫米或11毫米长的钛牙科植入物。使用共振频率分析仪来测量植入物放置时以及愈合2周，4周，6周，8周，10周和12周后的植入物稳定性商（ISQ）。种植体周围边缘骨水平的变化是通过在植入种植体时以及愈合4周，8周和12周后拍摄的数字X线胶片进行评估的。这项研究的初步结果表明，与上颌中的直种植体相比，圆锥形种植体的ISQ值更高，愈合趋势更好。对于下颌骨中的直形和圆锥形植入物，观察到相似的ISQ值和愈合趋势。在直形和圆锥形植入物之间未发现边缘骨丢失的显着差异。但是，在下颌骨中，在愈合12周后，锥形种植体的边缘骨损失比直种植体略多。

总之，ISQ的愈合趋势和边缘性骨丢失受种植体宏观设计和颌骨区域的影响。笔直的植入物在下颌骨和上颌骨中显示出相似的ISQ愈合趋势和边缘骨丢失。圆锥形植入物被证实对于维持上颌骨的植入物稳定性和边缘骨水平更有利。