Electrodialysis with porous membrane (EDPM) is a recently developed membrane separation process, in which one or more porous filtration membranes stacked in an electrodialysis cell. It is a promising technology for separation, purification or concentration of bioactive components for it associates the excellent properties of electrodialysis (ED), porous filtration membrane, and electrophoresis. There are a number of studies having attempted to optimize the performance of EDPM processing, however, it still has some limitations involving low productivity with one pair of separation unit, membrane fouling and few applications on the fractionation of components with high molecular weight. This paper offers a comprehensive overview of recent studies devoted to EDPM, including principles, configurations, mathematical model regarding mass transfer, process performance optimization, membrane fouling and applications in as much detail as possible. In addition, a collection of other separation technologies based on electrophoresis at a preparative scale are presented to illustrate their limitations on the large-scale application. Some drawbacks of EDPM have been put forward. To achieve full scale applications of EDPM, there are still many issues to overcome. Finally, an outlook for prospective development of EDPM technology is given.

多孔膜电渗析（EDPM）是最近开发的膜分离工艺，其中一个或多个多孔滤膜堆叠在电渗析池中。这是一种分离，纯化或浓缩生物活性成分的有前途的技术，因为它结合了电渗析（ED），多孔滤膜和电泳的优异性能。有许多研究试图优化EDPM处理的性能，但是，它仍然存在一些局限性，包括一对分离单元的低生产率，膜污染以及在高分子量组分的分离方面的应用很少。本文提供了有关EDPM的最新研究的全面概述，包括原理，配置，有关传质的数学模型，过程性能优化，膜污染和应用尽可能详细。此外，还提供了一些基于电泳的制备规模的其他分离技术的集合，以说明其在大规模应用中的局限性。提出了EDPM的一些缺点。为了实现EDPM的全面应用，仍然需要解决许多问题。最后，给出了EDPM技术的前瞻性展望。仍然有许多问题需要克服。最后，给出了EDPM技术的前瞻性展望。仍然有许多问题需要克服。最后，给出了EDPM技术的前瞻性展望。