Surface plasmon resonance (SPR) devices are known to be able to detect traces of chemicals and can, therefore, be applied to a variety of applications. However, in order to define the sensitivity of such a device, one must obtain its minimum detectability. Nevertheless, the standard way to define the lower limit of detectability of an SPR device has not yet been established. In this paper, we propose a method to define the minimum detectability of SPR devices based on the 3 σ rule. We measured the response of an SPR device by varying the concentrations of a single neutral analyte (ethylene glycol in deionized water). Then, we successfully obtained its lower limit of detectability, based on the measured data and the 3 σ rule. Our method provides a standardized way to easily evaluate the quality of SPR devices.

中文翻译：

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使用 3σ 规则确定表面等离子体共振器件的最小可探测性

众所周知，表面等离子体共振 (SPR) 设备能够检测痕量的化学物质，因此可以应用于各种应用。然而，为了定义这种设备的灵敏度，必须获得其最低可检测性。然而，尚未建立定义 SPR 设备可检测性下限的标准方法。在本文中，我们提出了一种基于 3 σ 规则来定义 SPR 设备的最小可检测性的方法。我们通过改变单一中性分析物（去离子水中的乙二醇）的浓度来测量 SPR 设备的响应。然后，我们根据实测数据和 3 σ 规则成功获得了其可检测性下限。我们的方法提供了一种标准化的方法来轻松评估 SPR 设备的质量。