The aim of our study was to compare the course of TBE in children and adults. A retrospective analysis of the medical records of 669 patients was performed. The patients were categorized into 2 groups: Group I with 68 children and group II with 601 adults. TBE symptoms in children were milder compared with adults, with meningitis in 97% of cases. In adults, meningoencephalitis and meningoencephalomyelitis made up 49.26% of cases. Nausea and vomiting are more frequent in children, while neurological manifestations are more frequent in adults. There were no differences in CSF pleocytosis at the onset of disease in both groups, while CSF protein concentration was higher in adults. Children treated with corticosteroids over 7 days had higher checkup pleocytosis than pleocytosis at the onset of disease compared with adults. Corticosteroid use prolongs the disease duration but does not influence the development of TBE sequelae. Children had more favourable outcomes than adult patients.

我们研究的目的是比较儿童和成人的TBE病程。对669例患者的病历进行回顾性分析。将患者分为两组：第一组有68名儿童，第二组有601名成人。与成人相比，儿童的TBE症状较轻，其中97％的病例患有脑膜炎。在成人中，脑膜脑炎和脑膜脑脊髓炎占病例的49.26％。恶心和呕吐在儿童中更常见，而神经系统表现在成年人中更常见。两组在发病时脑脊液的胞吞作用均无差异，而成年人中脑脊液的蛋白浓度较高。与成人相比，在疾病发作时接受皮质类固醇激素治疗超过7天的儿童，其体格检查有很多。使用皮质类固醇可延长疾病持续时间，但不影响TBE后遗症的发展。儿童比成年患者有更好的预后。