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Severe cases of seasonal influenza and detection of seasonal A(H1N2) in Russia in 2018-2019.
Archives of Virology ( IF 2.7 ) Pub Date : 2020-06-10 , DOI: 10.1007/s00705-020-04699-z
Natalia P Kolosova 1 , Tatyana N Ilyicheva 1 , Alexey V Danilenko 1 , Svetlana V Svyatchenko 1 , Natalia I Goncharova 1 , Julia A Bulanovich 1 , Polina Yu Torzhkova 1 , Alexander G Durymanov 1 , Andrei S Gudymo 1 , Alexander N Shvalov 1 , Ivan M Susloparov 1 , Tatyana V Tregubchak 1 , Elena V Gavrilova 1 , Rinat A Maksyutov 1 , Alexander B Ryzhikov 1
Affiliation  

Data obtained from monitoring cases of severe influenza, cases of vaccinated individuals, and unique cases were used to describe influenza viruses that circulated in Russia in the 2018–2019 epidemic season. A high proportion of the mutations D222G/N in A(H1N1)pdm09 HA was detected in fatal cases. Viruses of the B/Victoria lineage with deletions in HA were detected in Russia, and a reassortant seasonal influenza A(H1N2) virus was identified. A C-terminal truncation in the NS1 protein was detected in a substantial proportion of A(H3N2) viruses.



中文翻译:

2018-2019年俄罗斯严重季节性流感病例和季节性A(H1N2)检测。

通过监测严重流感病例,接种疫苗病例和特殊病例获得的数据被用来描述俄罗斯在2018-2019流行季节传播的流感病毒。在致命病例中,在A(H1N1)pdm09 HA中检测到很高比例的D222G / N突变。在俄罗斯检测到B / Victoria谱系中HA缺失的病毒,并鉴定了重配的季节性甲型H1N2流感病毒。在很大比例的A(H3N2)病毒中检测到NS1蛋白的C端截短。

更新日期:2020-06-10
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