Suitable micropumping methods for flow control represent a major technical hurdle in the development of microfluidic systems for point-of-care testing (POCT). Passive micropumping for point-of-care microfluidic systems provides a promising solution to such challenges, in particular, passive micropumping based on capillary force and air transfer based on the air solubility and air permeability of specific materials. There have been numerous developments and applications of micropumping techniques that are relevant to the use in POCT. Compared with active pumping methods such as syringe pumps or pressure pumps, where the flow rate can be well-tuned independent of the design of the microfluidic devices or the property of the liquids, most passive micropumping methods still suffer flow-control problems. For example, the flow rate may be set once the device has been made, and the properties of liquids may affect the flow rate. However, the advantages of passive micropumping, which include simplicity, ease of use, and low cost, make it the best choice for POCT. Here, we present a systematic review of different types of passive micropumping that are suitable for POCT, alongside existing applications based on passive micropumping. Future trends in passive micropumping are also discussed.

中文翻译：

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微流体中的被动微泵用于即时测试。


用于流量控制的合适的微泵方法是开发用于即时检测（POCT）的微流体系统的主要技术障碍。用于护理点微流控系统的被动微泵为此类挑战提供了一种有前景的解决方案，特别是基于毛细管力的被动微泵以及基于特定材料的空气溶解度和透气性的空气传输。与 POCT 中的使用相关的微泵技术已经有许多发展和应用。与注射泵或压力泵等主动泵送方法相比，流量可以独立于微流体装置的设计或液体的特性进行良好调节，大多数被动微泵送方法仍然面临流量控制问题。例如，一旦装置制成，就可以设定流速，并且液体的性质可能影响流速。然而，被动微泵的优点包括简单、易于使用和低成本，使其成为 POCT 的最佳选择。在这里，我们对适合 POCT 的不同类型的被动微泵以及基于被动微泵的现有应用进行了系统回顾。还讨论了被动微泵的未来趋势。