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Dielectric properties of healthy and diabetic alloxan-induced lenses in rabbits.
Bioelectrochemistry ( IF 4.8 ) Pub Date : 2020-06-09 , DOI: 10.1016/j.bioelechem.2020.107583
E Marzec 1 , M Nowakowska De Rossi 2 , S Paolucci 2 , J Olszewski 1
Affiliation  

The dielectric properties of the eye lens were studied for healthy and alloxane-induced diabetic rabbits in the frequency range from 500 Hz to 100 kHz electric field and temperatures from 25 to 50 °C. In the full temperature range, the average relative permittivity and dielectric loss values for a healthy lens are lower than those recorded for diabetic tissue. Dielectric relaxation of polar amino acids on the alpha-crystallin surface with a characteristic frequency of 7 kHz in the range of 25–50 °C for healthy and diabetic samples is accompanied by the activation energy of proton conductivity with an average values of 33 and 39 kJ mol−1, respectively. The permittivity decrement, which characterizes the size of the dielectric dispersion with a central relaxation time of 0.023 ms for a diabetic sample, is more than twice as high as for a healthy sample. Measurements on the rabbit eye lens were carried out at ambient temperature above and below the physiological range, since these conditions provide an appropriate pattern of dielectric behavior for the diagnosis of clinical dysfunction of the human lens.



中文翻译:

健康和糖尿病四氧嘧啶诱导的兔晶状体的介电性能。

在500 Hz至100 kHz电场的频率范围和25至50°C的温度范围内,研究了健康和四氧六环诱发的糖尿病兔子的眼镜的介电性能。在整个温度范围内,健康镜片的平均相对介电常数和介电损耗值低于糖尿病组织记录的平均相对介电常数和介电损耗值。对于健康和糖尿病患者,α-晶状体蛋白表面上极性氨基酸的介电弛豫(特征频率为7 kHz,在25–50°C范围内)伴随着质子电导率的活化能,平均值为33和39 kJ摩尔-1, 分别。介电常数的下降是正常样品的两倍,介电常数下降的特征在于介电分散体的大小,中心松弛时间为0.023 ms。在兔眼晶状体上的测量是在高于和低于生理范围的环境温度下进行的,因为这些条件为诊断人晶状体的功能障碍提供了适当的介电行为模式。

更新日期:2020-06-09
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