The key options for the synthesis of functionalized pillar[5]arenes and their applications in electrochemical sensors and biosensors are considered. Examples of using the macrocycle as an electron transfer mediator, a reactant for the formation of host—guest complexes, and a carrier of biochemical receptors are given. Details of behavior and ways of inclusion of pillararenes into the surface layer of electrochemical sensors are indicated. The trends of further development of pillararene chemistry are discussed as applied to the problems of advancement of electrochemical sensors.

中文翻译：

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柱[5]芳烃平台上的电化学传感器和生物传感器

考虑了功能化柱[5]芳烃合成的关键选择及其在电化学传感器和生物传感器中的应用。给出了使用大环作为电子转移介质、形成宿主-客体复合物的反应物和生化受体载体的例子。指出了将柱芳烃包含在电化学传感器表面层中的行为细节和方式。针对电化学传感器的进步问题，讨论了柱芳烃化学进一步发展的趋势。