The hydraulic conductivity of the vitreous humor has been measured for the bovine eye. The experiment was carried out by placing it within upright cylindrical chamber, open at both ends, and letting its liquid content drain out of the bottom opening by gravity, through a 20μm nylon mesh filter. Additional negative pressure was provided at the exit by a hanging drainage tube. The diminishing vitreous volume was measured in terms of the height in the chamber and recorded as a function of time. The reduction in the vitreous liquid content also caused the hydraulic conductivity to reduce and this parameter was quantified on the basis of previously-developed theories of fibrous porous media that have been very well established. A theoretical model with a fully analytical expression for the vitreous volume undergoing drainage was developed and used as a least-squares best fit to deliver the initial hydraulic conductivity value of K 0/μ=(7.8 ± 3.1) × 10-12 m2 (Pa-s). The measurements were made with the hyaloid membrane intact and therefore represents an effective conductivity for the entire system, including possible variations within the vitreous.

中文翻译：

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玻璃体水力传导性的测量


已经测量了牛眼玻璃体液的水力传导率。实验是将其放置在两端开口的直立圆筒室内，通过20μm尼龙网过滤器，利用重力从底部开口排出液体。通过悬挂的引流管在出口处提供额外的负压。根据腔室中的高度测量逐渐减少的玻璃体体积并记录为时间的函数。玻璃液含量的减少也导致导水率降低，并且该参数是根据先前开发的已非常成熟的纤维多孔介质理论来量化的。开发了一个具有完整解析表达式的排水玻璃体积理论模型，并用作最小二乘最佳拟合，以提供初始水力传导率值 K 0/μ=(7.8 ± 3.1) × 10-12 m2 (Pa -s）。测量是在玻璃体膜完整的情况下进行的，因此代表了整个系统的有效电导率，包括玻璃体内可能的变化。