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A modular high-density μECoG system on macaque vlPFC for auditory cognitive decoding.
Journal of Neural Engineering ( IF 3.7 ) Pub Date : 2020-07-09 , DOI: 10.1088/1741-2552/ab9986
Chia-Han Chiang 1 , Jaejin Lee , Charles Wang , Ashley J Williams , Timothy H Lucas , Yale E Cohen , Jonathan Viventi
Affiliation  

Objective. A fundamental goal of the auditory system is to parse the auditory environment into distinct perceptual representations. Auditory perception is mediated by the ventral auditory pathway, which includes the ventrolateral prefrontal cortex (vlPFC). Because large-scale recordings of auditory signals are quite rare, the spatiotemporal resolution of the neuronal code that underlies vlPFC’s contribution to auditory perception has not been fully elucidated. Therefore, we developed a modular, chronic, high-resolution, multi-electrode array system with long-term viability in order to identify the information that could be decoded from μ ECoG vlPFC signals. Approach. We molded three separate μ ECoG arrays into one and implanted this system in a non-human primate. A custom 3D-printed titanium chamber was mounted on the left hemisphere. The molded 294-contact μ ECoG array was implanted subdurally over the vlPFC. μ ECoG activity was recorded w...

中文翻译:

猕猴vlPFC上的模块化高密度μECoG系统,用于听觉认知解码。

目的。听觉系统的基本目标是将听觉环境解析为不同的感知表示。听觉感知由腹侧听觉通路介导,其中包括腹侧前额叶皮层(vlPFC)。由于听觉信号的大规模记录非常少见,因此尚未完全阐明构成vIPFC对听觉感知的基础的神经元代码的时空分辨率。因此,我们开发了具有长期生存能力的模块化,长期,高分辨率,多电极阵列系统,以识别可以从μECoG vlPFC信号中解码的信息。方法。我们将三个独立的μECoG阵列模制成一个,并将该系统植入到非人类的灵长类动物中。定制的3D打印钛室安装在左半球上。将成型的294触点μECoG阵列硬膜下植入vIPFC。记录了μECoG活性
更新日期:2020-07-10
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