Fibroblastic reticular cells (FRCs) are a necessary immunological component for T cell health. These myofibroblasts are specialized for immune cell support and develop in locations where T and B lymphocyte priming occurs, usually secondary lymphoid organs, but also tertiary lymphoid structures and sites of chronic inflammation. This review describes their dual supportive and suppressive functions and emerging evidence on the co-ordination required to balance these competing roles.

中文翻译：

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淋巴组织中的成纤维细胞 T 细胞生态位。

成纤维细胞网状细胞 (FRC) 是 T 细胞健康所必需的免疫成分。这些肌成纤维细胞专门用于免疫细胞支持，并在 T 和 B 淋巴细胞启动的部位发育，通常是二级淋巴器官，但也有三级淋巴结构和慢性炎症部位。本综述描述了它们的双重支持和抑制功能以及平衡这些竞争角色所需的协调的新证据。