Background Nutritional ergogenic aids are commonly used to boost physiological adaptations to exercise and promote greater fitness gains. However, there is a paucity of data about multi-ingredient pre-workout supplementation (MIPS). Therefore, the aim of the present study was to investigate the acute effects of MIPS on the oxidative, glycolytic and ATP-CP energy systems contribution, time spent above 90% V̇O 2max (T90% V̇O 2max ), excess post-exercise oxygen consumption (EPOC) magnitude, number of efforts and time to exhaustion during a high-intensity interval exercise (HIIE) session. Methods Twelve physically-active and healthy men completed the HIIE sessions that involved running bouts of 15 s on the treadmill at 120% of the maximum aerobic speed (MAS), interspersed with 15 s of passive recovery. Blood lactate was collected at immediately post, 3, 5, and 7 min post exercise. The contribution of ATP-CP, glycolytic and oxidative systems was analyzed at rest, during the HIIE sessions and for 20 min post. Performance variables (time to exhaustion, number of efforts) and oxygen consumption were also analyzed. Results MIPS significantly increased the number of efforts performed (MIPS: 41 ± 10 vs Placebo: 36 ± 12, p = 0.0220) and time to exhaustion (MIPS: 20.1 ± 6 min vs Placebo: 17 ± 5 min, p = 0.0226). There was no difference between supplements for both T90% V̇O 2max ( p = 0.9705) and EPOC ( p = 0.4930). Consuming MIPS significantly increased the absolute oxidative energy system contribution by 23.8% ( p = 0.0163) and the absolute ATP-CP contribution by 28.4% ( p = 0.0055) compared to placebo. There was only a non-significant tendency for a higher glycolytic system contribution after MIPS ingestion ( p = 0.0683). Conclusion Acute MIPS ingestion appears effective at increasing both aerobic and anaerobic alactic energy contribution and time to exhaustion during a HIIE protocol.

中文翻译：

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多成分运动前补充剂改变能量系统贡献并提高身体活跃个体在高强度间歇运动期间的表现：一项双盲和安慰剂对照研究

背景 营养增效剂通常用于促进生理对运动的适应并促进更大的健康收益。然而，关于多成分运动前补充剂 (MIPS) 的数据很少。因此，本研究的目的是研究 MIPS 对氧化、糖酵解和 ATP-CP 能量系统贡献的急性影响、超过 90% V̇O 2max (T90% V̇O 2max ) 的时间、运动后过量耗氧量（ EPOC) 在高强度间歇锻炼 (HIIE) 会议期间的强度、努力次数和疲劳时间。方法 12 名身体活跃且健康的男性完成了 HIIE 课程，包括在跑步机上以 120% 的最大有氧速度 (MAS) 跑步 15 秒，中间穿插 15 秒的被动恢复。立即采集血乳酸，运动后 3、5 和 7 分钟。ATP-CP、糖酵解和氧化系统的贡献在休息时、HIIE 会议期间和 20 分钟后进行分析。还分析了性能变量（疲劳时间、努力次数）和耗氧量。结果 MIPS 显着增加了执行的努力次数（MIPS：41 ± 10 与安慰剂：36 ± 12，p = 0.0220）和疲劳时间（MIPS：20.1 ± 6 分钟与安慰剂：17 ± 5 分钟，p = 0.0226）。T90% V̇O 2max (p = 0.9705) 和 EPOC (p = 0.4930) 的补充剂之间没有差异。与安慰剂相比，服用 MIPS 显着增加了 23.8% (p = 0.0163) 的绝对氧化能量系统贡献和 28.4% (p = 0.0055) 的绝对 ATP-CP 贡献。摄入 MIPS 后糖酵解系统的贡献没有显着趋势（p = 0.0683）。结论 急性 MIPS 摄入在增加 HIIE 方案期间的有氧和无氧无氧能量贡献和疲劳时间方面似乎是有效的。