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Matrix metalloproteinase inhibitor and sunscreen effective compounds from Rumex crispus L.: isolation, identification, bioactivity and molecular docking study.
Phytochemical Analysis ( IF 3.0 ) Pub Date : 2020-06-03 , DOI: 10.1002/pca.2948
Mine Uzun 1 , Zuhal Guvenalp 2 , Cavit Kazaz 3 , L Omur Demirezer 1
Affiliation  

Rumex (Polygonaceae) species are widely grown worldwide and their main compounds are anthranoids, tannins, naphthalenes and flavonoids. Matrix metalloproteinase (MMP) enzymes that cause the breakdown of the extracellular matrix and harmful ultraviolet (UV) rays are two important causes of skin ageing. Although there have been many studies on anthraquinones, there are not many studies on their anti‐ageing effects.

中文翻译:

Rumex crispus L.的基质金属蛋白酶抑制剂和防晒有效化合物:分离,鉴定,生物活性和分子对接研究。

朗美(Polygonaceae)种在世界范围内广泛种植,其主要化合物是类蒽,单宁,萘和类黄酮。导致细胞外基质分解和有害紫外线(UV)的基质金属蛋白酶(MMP)是皮肤老化的两个重要原因。尽管对蒽醌的研究很多,但对它们的抗衰老作用的研究却很少。
更新日期:2020-06-03
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