Summary Preimplantation embryos frequently contain binucleated cells, but reports differ as to whether binucleation affects development and whether such embryos should be used clinically. In this Point Of View article, we propose a possible explanation for this disparity: binucleation can arise by distinct routes, one that produces healthy blastomeres and one that directly threatens embryo viability.

中文翻译：

---

胚胎双核化的影响取决于其起源

总结 植入前胚胎通常含有双核细胞，但关于双核是否影响发育以及此类胚胎是否应用于临床的报道各不相同。在这篇观点文章中，我们对这种差异提出了一种可能的解释：双核可以通过不同的途径产生，一种产生健康的卵裂球，另一种直接威胁胚胎活力。