Biomarkers diagnose, predict or assess the risk of disease, and studies of the effects of genetic variation on biomarker phenotypes in the general population complement studies on patients diagnosed with disease. This paper traces the evolution of studies on biomarker genetics over the past 40 years through examples drawn from the work of Professor Martin and his colleagues.

中文翻译：

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生化表型遗传学

生物标志物可诊断、预测或评估疾病风险，而对一般人群中遗传变异对生物标志物表型影响的研究补充了对被诊断患有疾病的患者的研究。本文通过 Martin 教授及其同事的工作示例，追溯了过去 40 年来生物标志物遗传学研究的演变。