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Electrochemiluminescent detection of glucose in human serum by BODIPY-based chemodosimeters for hydrogen peroxide using accelerated self-immolation of boronates.
Chemical Communications ( IF 4.3 ) Pub Date : 2020-06-08 , DOI: 10.1039/d0cc03315d
Yon Namkoong 1 , Jinrok Oh , Jong-In Hong
Affiliation  

BODIPY-based ECL chemodosimeters were developed for the detection of hydrogen peroxide. The reactivity of boronate towards hydrogen peroxide was enhanced by adjacent fluorine atoms. In combination with glucose oxidase, a fluorine-substituted probe successfully quantified the glucose level in human serum, providing its potential as a versatile tool in point-of-care testing applications.

中文翻译:

基于BODIPY的化学计量器使用硼酸盐的加速自消灭,通过过氧化氢的化学发光检测人血清中的葡萄糖。

基于BODIPY的ECL化学计量仪被开发用于检测过氧化氢。相邻的氟原子增强了硼酸酯对过氧化氢的反应性。与葡萄糖氧化酶结合使用,氟取代的探针成功地定量了人血清中的葡萄糖水平,为其在即时检验应用中的多功能工具提供了潜力。
更新日期:2020-07-09
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