Objective: To examine the naturalistic response to and cardiovascular side effects of stimulant medication in older adults with ADHD. Methods: Electronic Health Record (EHR) data of adult patients with ADHD (≥55 years) at the specialized PsyQ outpatient clinic for adult ADHD (n = 113, 55-79 years) were collected. Response, cardiovascular status, side effects, and provided medical care before and after the first ADHD medication dose have been recorded. Results: A total of 65% of the patients reported positive response to the medication, and 42% of the patients quit their medication due to side effects or nonresponse. There was a small but significant decrease in weight and increase in heart rate before and after methylphenidate use. Conclusion: Our results indicate that the use of stimulants may be a relatively safe and effective treatment for older adults with ADHD, under the condition that the cardiovascular parameters are monitored before and during pharmacological treatment. Randomized controlled trials (RCTs) are needed to confirm these findings.

目的：检查患有 ADHD 的老年人对兴奋剂药物的自然反应和心血管副作用。方法：收集了成人 ADHD 专科 PsyQ 门诊（n = 113，55-79 岁）的ADHD 成年患者（≥55 岁）的电子健康记录（EHR）数据。记录了第一次 ADHD 药物剂量前后的反应、心血管状态、副作用和提供的医疗护理。结果：共有 65% 的患者报告对药物有积极反应，42% 的患者因副作用或无反应而停止服药。在使用哌甲酯之前和之后，体重和心率都有轻微但显着的下降。结论：我们的结果表明，在药物治疗前和药物治疗期间监测心血管参数的情况下，使用兴奋剂可能是老年 ADHD 患者相对安全和有效的治疗方法。需要随机对照试验 (RCT) 来证实这些发现。