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Conservation of brain connectivity and wiring across the mammalian class.
Nature Neuroscience ( IF 25.0 ) Pub Date : 2020-06-08 , DOI: 10.1038/s41593-020-0641-7
Yaniv Assaf 1, 2 , Arieli Bouznach 3 , Omri Zomet 4 , Assaf Marom 5 , Yossi Yovel 2, 6, 7
Affiliation  

Over 100 years ago, Ramon y Cajal hypothesized that two forces played a role in the evolution of mammalian brain connectivity: minimizing wiring costs and maximizing conductivity speed. Using diffusion MRI, we reconstructed the brain connectomes of 123 mammalian species. Network analysis revealed that both connectivity and the wiring cost are conserved across mammals. We describe a conservation principle that maintains the overall connectivity: species with fewer interhemispheric connections exhibit better intrahemispheric connectivity.



中文翻译:

保护整个哺乳动物类别的大脑连接性和连线。

一百多年前,拉蒙·卡哈尔(Ramon y Cajal)推测,两种力在哺乳动物大脑连接性的进化中起着作用:最小化布线成本和最大化电导率速度。使用扩散核磁共振成像,我们重建了123个哺乳动物物种的大脑连接组。网络分析表明,哺乳动物之间的连接性和布线成本均得到了保留。我们描述了一种保持总体连通性的保护原则:半球间连接较少的物种表现出更好的半球内连通性。

更新日期:2020-06-08
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