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Shape Memory Tube Plug for Fine-control of Intraocular Pressure by Glaucoma Devices
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2020-06-07 , DOI: 10.1021/acsbiomaterials.0c00649
Won Taek Oh 1 , Jung Bok Lee 2 , Wungrak Choi 3 , Hyoung Won Bae 3 , Chang Soo Kim 4 , Chan Yun Kim 3 , Hak-Joon Sung 5
Affiliation  

As a standard approach to treating glaucoma, a silicone tube device is inserted into the eye to drain water and thereby lower the intraocular pressure (IOP). However, the fixed diameter of the tube often results in too much initial water drain. Suture-sheaving of the outer tube wall also leads to random IOP drops over time. In this study, self-expansion of the inner tube diameter was achieved by inserting a shape memory tube into the silicone tube. The difference in controlling small to large IOP drops before and after tube diameter expansion was demonstrated via computational modeling, a flow pumping system, and rabbit experiments.

中文翻译:

用于青光眼装置精细控制眼压的形状记忆管塞

作为治疗青光眼的标准方法,将硅胶管设备插入眼睛以排干水,从而降低眼内压(IOP)。但是,管子的固定直径通常会导致过多的初始排水。外管壁的缝合线脱落还会导致随时间推移IOP随机下降。在这项研究中,通过将形状记忆管插入硅胶管中来实现内管直径的自膨胀。通过计算模型,流量泵系统和兔实验证明了在管径扩大之前和之后控制小到大IOP滴的差异。
更新日期:2020-07-13
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