Research shows decreased brain region activity in the right temporo-parietal junction (rTPJ) in people with migraine headache relative to headache-free controls when performing an orienting visuospatial attention task. Functional inactivation of the rTPJ has been associated with rightward performance deviations on laterality-based attention Landmark (LM) and greyscale (GRE) tasks in individuals with unilateral neglect and heightened activation in the rTPJ is associated with leftward deviation, known as pseudoneglect, in controls on these tasks. Given this, we investigated whether migraineurs would lack the leftward deviation found in headache-free controls on visuospatial attention tasks. 36 migraineurs and 38 controls were presented with LM and GRE tasks. Response bias scores showed a significant difference in responses between groups (p = 0.036) on the GRE, a luminance-based task, but not on the LM, a size-based task (p = 0.826). This study is the first to show laterality-based attentional differences in migraineurs, as compared to controls. Specifically, migraineurs were found to have smaller leftward biases on luminance-based visuospatial attention tasks, as compared to controls, aligning with previous research suggesting that migraine may be having an impact on a variety of attention tasks in migraineurs in between headache attacks.

研究表明，与偏头痛患者相比，偏头痛患者在进行定向视觉空间注意任务时，其右颞-顶叶接合处（rTPJ）的大脑区域活动减少。rTPJ的功能失活与单侧忽视个体中基于偏侧性注意地标（LM）和灰度（GRE）任务的向右性能偏差有关，而rTPJ中增强的激活与控件中的向左偏差（称为伪忽视）相关在这些任务上。鉴于此，我们调查了偏头痛患者是否会缺乏在视觉空间注意任务的无头痛控制中发现的左偏。向36位移民和38位控制人员介绍了LM和GRE任务。回应偏差得分显示各组之间的回应有显着差异（p  = 0.036）在GRE（基于亮度的任务）上，而不在LM（基于大小的任务）上（p  = 0.826）。这项研究是第一个显示偏头痛患者与对照组相比基于偏侧性的注意力差异的研究。具体而言，与对照相比，偏头痛被发现与基于亮度的视觉空间视觉注意任务相比，偏头痛左偏较小，这与先前的研究表明偏头痛在头痛发作之间可能对偏头痛的多种注意任务产生了影响。