当前位置: X-MOL 学术Eur. J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Triethyl Phosphite/Benzoyl Peroxide Mediated Reductive Dealkylation of O‐Benzoylhydroxylamines: A Cascade Synthesis of Secondary Amides
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-06-08 , DOI: 10.1002/ejoc.202000611
Balakrishna Aegurla 1 , Ram D. Mandle 1 , Prasad G. Shinde 2 , Ratan S. Parit 2 , Sanjay P. Kamble 1 , Arumugam Sudalai 1 , Beeran Senthilkumar 2
Affiliation  

An efficient and operationally simple protocol for the synthesis of 2° amides via reductive benzoylation dealkylation of O‐benzoylhydroxylamines (O‐BHA), by using triethyl phosphite as a reducing agent and benzoyl peroxide as an oxidizing agent is described.
image


中文翻译:

亚磷酸三乙酯/过氧化苯甲酰介导的邻苯甲酰羟胺的还原脱烷基作用:仲酰胺的级联合成

描述了一种有效且操作简单的方案,该方案通过使用亚磷酸三乙酯作为还原剂和过氧化苯甲酰作为氧化剂,通过O-苯甲酰羟胺(O- BHA)的还原性苯甲酰化脱烷基化反应来合成2°酰胺。
图片
更新日期:2020-07-16
down
wechat
bug