In a recent issue of Nature, Lammert et al. demonstrate that DNA damage drives AIM2-mediated pyroptosis during normal brain development, preventing anxiety-like behaviors acquisition in adults and revealing an important role for non-apoptotic mechanisms of cell death during neurodevelopment.

中文翻译：

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细胞凋亡以神经发育为目标。

在最近出版的“自然”杂志中，Lammert等人。证明了DNA损伤在正常的大脑发育过程中驱动AIM2介导的细胞凋亡，防止成人获得类似焦虑的行为，并揭示了神经发育过程中细胞死亡的非凋亡机制的重要作用。