Two papers, published in Science and Nature, report inhibitiors selectively targeting distinct bromodomains of BET proteins. These advanced chemical tools facilitate functional understanding of epigenetic regulators in normal and disease states and enable development of new medicine potentially with lower toxicity.

中文翻译：

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小分子对不同溴结构域的选择性靶向。

发表在《科学与自然》（Science and Nature）上的两篇论文报道了抑制子选择性靶向BET蛋白的不同溴结构域。这些先进的化学工具可促进对正常状态和疾病状态的表观遗传调节剂的功能性了解，并能开发毒性更低的新药。