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Distance-controllable and direction-steerable opto-conveyor for targeting delivery
Photonics Research ( IF 6.6 ) Pub Date : 2020-06-05 , DOI: 10.1364/prj.388106
Zhen Che , Wenguo Zhu , Yaoming Huang , Yu Zhang , Linqing Zhuo , Pengpeng Fan , Zhibin Li , Huadan Zheng , Wenjin Long , Wentao Qiu , Yunhan Luo , Jun Zhang , Jinghua Ge , Jianhui Yu , Zhe Chen

Opto-conveyors have attracted widespread interest in various fields because of their non-invasive and non-contact delivery of micro/nanoparticles. However, the flexible control of the delivery distance and the dynamic steering of the delivery direction, although very desirable in all-optical manipulation, have not yet been achieved by opto-conveyors. Here, using a simple and cost-effective scheme of an elliptically focused laser beam obliquely irradiated on a substrate, a direction-steerable and distance-controllable opto-conveyor for the targeting delivery of microparticles is implemented. Theoretically, in the proposed scheme of the opto-conveyor, the transverse and longitudinal resultant forces of the optical gradient force and the optical scattering force result in the transverse confinement and the longitudinal transportation of microparticles, respectively. In this study, it is experimentally shown that the proposed opto-conveyor is capable of realizing the targeting delivery for microparticles. Additionally, the delivery distance of microparticles can be flexibly and precisely controlled by simply adjusting the irradiation time. By simply rotating the cylindrical lens, the proposed opto-conveyor is capable of steering the delivery direction flexibly within a large range of azimuthal angles, from −75° to 75°. This study also successfully demonstrated the real-time dynamic steering of the delivery direction from −45° to 45° with the dynamical rotation of the cylindrical lens. Owing to its simplicity, flexibility, and controllability, the proposed method is capable of creating new opportunities in bioassays as well as in drug delivery.

中文翻译:

用于目标递送的距离可控和方向可控的光传送带

光电传送带因其微/纳米粒子的非侵入性和非接触式传递而在各个领域引起了广泛的兴趣。然而,输送距离的灵活控制和输送方向的动态转向,虽然在全光操纵中非常理想,但光传送带尚未实现。在这里,使用椭圆聚焦激光束倾斜照射在基板上的简单且具有成本效益的方案,实现了用于微粒靶向递送的方向可控和距离可控的光传送机。理论上,在提出的光传送器方案中,光学梯度力和光学散射力的横向和纵向合力分别导致微粒的横向限制和纵向运输。在这项研究中,实验表明,所提出的光传送带能够实现微粒的靶向递送。此外,通过简单地调整照射时间,可以灵活、精确地控制微粒的输送距离。通过简单地旋转柱面透镜,所提出的光传送器能够在从 -75° 到 75° 的大方位角范围内灵活地控制输送方向。该研究还成功地证明了通过柱面透镜的动态旋转实现了输送方向从 -45° 到 45° 的实时动态转向。
更新日期:2020-06-05
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