Screening the antifungal activities of monoterpenes and their isomers against Candida species.,Journal of Applied Microbiology

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Screening the antifungal activities of monoterpenes and their isomers against Candida species.
Journal of Applied Microbiology ( IF 3.2 ) Pub Date : 2020-06-07 , DOI: 10.1111/jam.14740
A Iraji ₁ , S Yazdanpanah ₂ , F Alizadeh ₂ , S Mirzamohammadi ₂ , Y Ghasemi ₃ , K Pakshir _{2,

4} , Y Yang ₅ , K Zomorodian _{2,

4}

Affiliation

Increasing the occurrence of non‐albicans Candida species with intrinsic or acquired resistance to antifungals as well as the emergence of multidrug Candida species coupled with the limited antifungal agents challenges the treatment of candidiasis. Consequently, a class of secondary metabolites of plants exhibiting decent antifungal activity. Therefore, this study aimed to evaluate the antifungal potential of various monoterpenes including Carvone, Limonene, Pinene, Menthone, Menthol, Camphor, Thujone, Citronellol, and Piperitone against standard and clinical isolates of Candida.

中文翻译：

筛选单萜及其异构体对念珠菌的抗真菌活性。

对内生性或后天性抗真菌药物耐药的非白色念珠菌种类的增加，以及多药假丝酵母菌种类的出现以及有限的抗真菌剂的出现，对念珠菌病的治疗提出了挑战。因此，一类植物的次级代谢产物表现出良好的抗真菌活性。因此，本研究旨在评估各种单萜类化合物（包括香芹酮，柠檬烯，Pin烯，薄荷酮，薄荷醇，樟脑，丁香，香茅醇和胡椒酮）对标准和临床念珠菌的抗真菌潜力。

更新日期：2020-06-07

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