Preterm delivery is the leading cause of neonatal mortality and contributes to delayed physical and cognitive development in children. At present, there is no efficient therapy to prevent preterm labor. A large body of evidence suggests that infections might play a significant and potentially preventable cause of premature birth. This work assessed the effects of erythropoietin (EPO) in a murine model of inflammation‐associated preterm delivery, which mimics central features of preterm infections in humans.

中文翻译：

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促红细胞生成素可防止 LPS 诱导的早产并增加后代的存活率。

早产是新生儿死亡的主要原因，并导致儿童身体和认知发育延迟。目前，还没有有效的治疗方法来预防早产。大量证据表明，感染可能是导致早产的一个重要且可能可预防的原因。这项工作评估了促红细胞生成素 (EPO) 在炎症相关早产小鼠模型中的作用，该模型模拟了人类早产感染的核心特征。