Neurogenic orthostatic hypotension (nOH) is a common comorbidity in patients with neurodegenerative diseases. It is associated with an increased risk of falls, incident cardiovascular disease, and all-cause mortality. There are over 5 million individuals in the U.S. with heart failure (HF) with an associated 50% mortality rate at 5 years. The prevalence of nOH and HF increase with age and, as the population continues to age, will be increasingly common comorbid conditions. Thus, the effective management of these conditions has important implications for public health. The management of orthostatic hypotension in the context of congestive heart failure is challenging due to the fact that the fundamental principles of management of these disease states are in opposition to each other. In this review, we will discuss the principles of management of nOH and HF and outline strategies for the effective treatment of these comorbid conditions.

中文翻译：

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心力衰竭患者神经源性直立性低血压的处理

神经源性直立性低血压 (nOH) 是神经退行性疾病患者常见的合并症。它与跌倒、心血管疾病和全因死亡率的风险增加有关。美国有超过 500 万人患有心力衰竭 (HF)，5 年死亡率为 50%。nOH 和 HF 的患病率随着年龄的增长而增加，并且随着人口不断老龄化，将成为越来越常见的合并症。因此，有效管理这些疾病对公共卫生具有重要意义。充血性心力衰竭背景下体位性低血压的管理具有挑战性，因为管理这些疾病状态的基本原则相互矛盾。在这次审查中，