Abstract In this paper we exposed samples of poly( l -lactide) (PLLA) extruded foil to ArF excimer laser (193 nm) radiation near the ablation threshold. The modified foil was immersed in the Simulated Body Fluid (SBF) at 37 °C for both short and long time (short term: up to 24 h, long term: up to four weeks). We described the physicochemical changes in PLLA before and after incubation in SBF. The laser irradiated PLLA incubated in SBF revealed turbidity on the irradiated surface. UV–Vis spectroscopy showed a remarkable decrease in transmittance for the irradiated PLLA incubated in SBF as compared to the non-irradiated PLLA incubated in SBF. Scanning electron microscopy proved the presence of minerals on the surface of PLLA in the laser irradiated area. The mineralization occurred only on the irradiated surface indicating that the process is selective. In the mineralized area a reduction of water contact angle was observed, suggesting a higher hydrophilicity of the surface. Moreover, a reduction in molecular weight was recorded in the long term incubation experiment for irradiated PLLA as compared to the unmodified sample. The samples were also investigated in terms of supramolecular changes in the material (DSC) and in terms of their thermal properties (TGA).

中文翻译：

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ArF准分子激光照射诱导模拟体液中PLLA选择性矿化的影响：具有骨组织工程潜力的定制复合材料

摘要 在本文中，我们将聚 (l-丙交酯) (PLLA) 挤压箔样品暴露于接近烧蚀阈值的 ArF 准分子激光 (193 nm) 辐射。将改性箔浸入 37°C 的模拟体液 (SBF) 中短期和长期（短期：长达 24 小时，长期：长达 4 周）。我们描述了在 SBF 中孵育前后 PLLA 的物理化学变化。在 SBF 中孵育的激光辐照 PLLA 显示辐照表面浑浊。UV-Vis 光谱显示，与在 SBF 中孵育的未辐照 PLLA 相比，在 SBF 中孵育的辐照 PLLA 的透射率显着降低。扫描电镜证明在激光照射区域的PLLA表面存在矿物质。矿化仅发生在辐照表面，表明该过程具有选择性。在矿化区域观察到水接触角的减小，表明表面具有更高的亲水性。此外，与未改性样品相比，经辐照的 PLLA 在长期孵育实验中记录到分子量降低。还根据材料的超分子变化 (DSC) 和热性能 (TGA) 对样品进行了研究。