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Pushing Cherenkov PET with BGO via coincidence time resolution classification and correction.
Physics in Medicine & Biology ( IF 3.5 ) Pub Date : 2020-06-04 , DOI: 10.1088/1361-6560/ab87f9
Nicolaus Kratochwil 1 , Stefan Gundacker , Paul Lecoq , Etiennette Auffray
Affiliation  

Bismuth germanate (BGO) shows good properties for positron emission tomography (PET) applications, but was substituted by the development of faster crystals like lutetium oxyorthosilicate (LSO) for time-of-flight PET (TOF-PET). Recent improvements in silicon photomultipliers (SiPMs) and fast readout electronics make it possible to access the Cherenkov photon signal produced upon 511 keV interaction, which makes BGO a cost-effective candidate for TOF-PET. Tails in the time-delay distribution, however, remain a challenge. These are mainly caused by the high statistical fluctuation on the Cherenkov photons detected. To select fast events with a high detected Cherenkov photon number, the signal rise time of the SiPM was used for discrimination. The charge, time delay and signal rise time was measured for two different lengths of BGO crystals coupled to FBK NUV-HD SiPMs and high frequency readout in a coincidence time resolution setup. The recorded events were divided into 5 ×...

中文翻译:

通过重合时间分辨率分类和校正,将Cherenkov PET与BGO配合使用。

锗酸铋(BGO)在正电子发射断层扫描(PET)应用中显示出良好的性能,但被更快的晶体如正硅酸lut(LSO)的发展所取代,成为飞行时间PET(TOF-PET)的替代品。硅光电倍增管(SiPM)和快速读出电子器件的最新改进使访问511 keV相互作用产生的Cherenkov光子信号成为可能,这使BGO成为TOF-PET的高性价比候选者。但是,延时分配中的尾巴仍然是一个挑战。这些主要是由检测到的切伦科夫光子的高统计波动引起的。为了选择具有高检测到的切伦科夫光子数的快速事件,将SiPM的信号上升时间用于判别。费用,在符合时间分辨率设置的情况下,针对耦合到FBK NUV-HD SiPM的两种不同长度的BGO晶体测量了时间延迟和信号上升时间。记录的事件分为5×...
更新日期:2020-06-04
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