Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, we describe a pathway wherein sleep fragmentation raises inflammatory-related white blood cell counts (neutrophils and monocytes), thereby increasing atherosclerosis severity, even when other common risk factors have been accounted for. Improving sleep quality may thus represent one preventive strategy for lowering inflammatory status and thus atherosclerosis risk, reinforcing public health policies focused on sleep health.

中文翻译：

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睡眠中断预示着血管硬化。

为什么睡眠质量差会导致动脉粥样硬化？在超过 1,600 人的不同样本中，我们描述了一种途径，其中睡眠碎片化会增加炎症相关的白细胞计数（中性粒细胞和单核细胞），从而增加动脉粥样硬化的严重程度，即使考虑到其他常见的风险因素也是如此。因此，改善睡眠质量可能代表一种降低炎症状态和动脉粥样硬化风险的预防策略，加强专注于睡眠健康的公共卫生政策。