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Low rate of azole resistance in cases of avian aspergillosis in Germany.
Medical Mycology ( IF 2.7 ) Pub Date : 2020-06-04 , DOI: 10.1093/mmy/myaa045
Amelia E Barber 1 , Sandra Scheufen 1 , Grit Walther 2 , Oliver Kurzai 1, 2 , Volker Schmidt 3
Affiliation  

Aspergillosis is the most common fungal disease of the avian respiratory tract. Due to delayed diagnosis and treatment failure, the outcome of these infections is often poor. We investigate 159 cases of avian aspergillosis among captive birds in Germany to define clinical features as well as the frequency of in vitro triazole resistance. Adult birds were more likely to present with clinical signs compared to juvenile birds, and dyspnoea was the most common clinical sign, present in 53% of birds. Molecular species identification indicated that all infections were caused by Aspergillus fumigatus. Only one of 159 independent isolates was azole resistant.

中文翻译:

德国禽曲霉病患者对唑的耐药率较低。

曲霉病是禽呼吸道最常见的真菌病。由于延迟的诊断和治疗失败,这些感染的结果通常很差。我们调查了德国圈养鸟类中的159例禽曲霉病,以定义临床特征以及体外对三唑耐药的频率。与幼鸟相比,成年鸟更容易出现临床体征,呼吸困难是最常见的临床体征,占53%。分子种类鉴定表明,所有感染都是由烟曲霉引起的。159个独立分离株中只有1个对唑具有抗性。
更新日期:2020-06-04
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