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SnpHub: an easy-to-set-up web server framework for exploring large-scale genomic variation data in the post-genomic era with applications in wheat.
GigaScience ( IF 11.8 ) Pub Date : 2020-06-05 , DOI: 10.1093/gigascience/giaa060
Wenxi Wang 1 , Zihao Wang 1 , Xintong Li 1 , Zhongfu Ni 1 , Zhaorong Hu 1 , Mingming Xin 1 , Huiru Peng 1 , Yingyin Yao 1 , Qixin Sun 1 , Weilong Guo 1
Affiliation  

The cost of high-throughput sequencing is rapidly decreasing, allowing researchers to investigate genomic variations across hundreds or even thousands of samples in the post-genomic era. The management and exploration of these large-scale genomic variation data require programming skills. The public genotype querying databases of many species are usually centralized and implemented independently, making them difficult to update with new data over time. Currently, there is a lack of a widely used framework for setting up user-friendly web servers to explore new genomic variation data in diverse species.

中文翻译:


SnpHub:一个易于设置的 Web 服务器框架,用于探索后基因组时代的大规模基因组变异数据并在小麦中应用。



高通量测序的成本正在迅速下降,使研究人员能够在后基因组时代研究数百甚至数千个样本的基因组变异。这些大规模基因组变异数据的管理和探索需要编程技能。许多物种的公共基因型查询数据库通常是集中式的并且独立实施,使得它们难以随着时间的推移用新数据进行更新。目前,缺乏广泛使用的框架来建立用户友好的网络服务器来探索不同物种的新基因组变异数据。
更新日期:2020-06-05
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