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The Project Baseline Health Study: a step towards a broader mission to map human health.
npj Digital Medicine ( IF 12.4 ) Pub Date : 2020-06-05 , DOI: 10.1038/s41746-020-0290-y
Kristine Arges 1 , Themistocles Assimes 2 , Vikram Bajaj 2 , Suresh Balu 1 , Mustafa R Bashir 1 , Laura Beskow 3 , Rosalia Blanco 1 , Robert Califf 4 , Paul Campbell 1 , Larry Carin 1 , Victoria Christian 1 , Scott Cousins 1 , Millie Das 2 , Marie Dockery 1 , Pamela S Douglas 1 , Ashley Dunham 1 , Julie Eckstrand 1 , Dominik Fleischmann 2 , Emily Ford 1 , Elizabeth Fraulo 1 , John French 1 , Sanjiv S Gambhir 2 , Geoffrey S Ginsburg 1 , Robert C Green 5 , Francois Haddad 2 , Adrian Hernandez 1 , John Hernandez 6 , Erich S Huang 1 , Glenn Jaffe 1 , Daniel King 1 , Lynne H Koweek 1 , Curtis Langlotz 2 , Yaping J Liao 2 , Kenneth W Mahaffey 2 , Kelly Marcom 1 , William J Marks 2, 4 , David Maron 2 , Reid McCabe 1 , Shannon McCall 1 , Rebecca McCue 2 , Jessica Mega 4 , David Miller 4 , Lawrence H Muhlbaier 1 , Rajan Munshi 2 , L Kristin Newby 1 , Ezra Pak-Harvey 1 , Bray Patrick-Lake 1 , Michael Pencina 1 , Eric D Peterson 1 , Fatima Rodriguez 2 , Scarlet Shore 4 , Svati Shah 1 , Steven Shipes 1 , George Sledge 2 , Susie Spielman 2 , Ryan Spitler 2 , Terry Schaack 7 , Geeta Swamy 1 , Martin J Willemink 2 , Charlene A Wong 1
Affiliation  

The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.



中文翻译:

项目基线健康研究:朝着绘制人类健康图的更广泛使命迈出的一步。

基线健康研究项目 (PBHS) 的启动旨在通过全面了解个人健康及其与更广泛人群的关系来绘制人类健康图。该研究将有助于创建一个生物医学信息系统,该系统可以解释生物、行为、环境和社会系统之间高度复杂的相互作用。PBHS​​ 是一项前瞻性、多中心、纵向队列研究,旨在招募数千名具有不同背景、代表整个健康领域的参与者。将使用临床、分子、成像、传感器、自我报告、行为、心理、环境和其他健康相关测量对登记的参与者进行连续评估。最初的深度表型队列将为大型、扩展的虚拟队列的开发提供信息。PBHS​​ 将通过整合最先进的测试、纵向监测和参与者参与,并致力于开发改进的数据共享和分析平台,为精准健康和医学做出贡献。

更新日期:2020-06-05
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