ABSTRACT The aim of this study was to evaluate the effect of intraruminal boluses with sulfamethazine (SM) and selenium (Se) on goat kids naturally infected with Eimeria. Twenty goat kids were selected with an average body weight (BW) of 13.7 kg. They were grouped as follows (n = 5 animals per group). BC: dosed with boluses without drugs; BSM: dosed with boluses containing 4 g of SM; BSe: dosed with boluses containing 90 mg of Se; BSMSe: dosed with boluses with 4 g of SM + 90 mg of Se. All animals showed the presence of the boluses at 10 d after dosing by radiography. DMI/BW at the beginning of the experiment was low: 0.76% in BC and 0.86% in the dosed groups. At the end of the experiment there was an increase: 1.36% in BC and 1.54% in the dosed groups (P > 0.05). BSMSe had the lowest percentage of Eimeria spp (P < 0.05). There were differences between the Eimeria species found before and after the treatments. It was observed that BSM and BSMSe decreased the number of oocysts from 7 to 28 d (P < 0.05). BSMSe had the highest content of blood SM and Se (P < 0.05). The histological alterations were loss of the epithelium and villous atrophy.

中文翻译：

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在自然感染艾美球虫的山羊孩子中评价用磺胺二甲嘧啶和硒给药的瘤胃内推注。

摘要 本研究的目的是评估含有磺胺二甲嘧啶 (SM) 和硒 (Se) 的瘤胃内推注对自然感染艾美球虫的山羊孩子的影响。选择了 20 只山羊孩子，平均体重 (BW) 为 13.7 公斤。它们按如下分组（每组 n = 5 只动物）。BC：无药物推注给药；BSM：服用含有 4 克 SM 的丸剂；BSe：以含有 90 mg Se 的推注给药；BSMSe：以 4 克 SM + 90 毫克硒推注给药。所有动物在给药后第 10 天通过放射照相显示存在大丸剂。实验开始时的 DMI/BW 很低：BC 为 0.76%，给药组为 0.86%。在实验结束时，BC 增加了 1.36%，给药组增加了 1.54% (P > 0.05)。BSMSe 的艾美球虫百分比最低 (P < 0.05)。处理前后发现的艾美球虫物种之间存在差异。观察到 BSM 和 BSMSe 使卵囊数量从 7 天减少到 28 天（P < 0.05）。BSMSe 的血 SM 和 Se 含量最高（P < 0.05）。组织学改变是上皮细胞丢失和绒毛萎缩。