The consumption of ayahuasca, a brew prepared from the decoction of two Amazon plants, has increased worldwide in the last decades. This fact raised questions about the safety in its oral administration. In this sense, information concerning the chemical composition of ayahuasca is essential to find a comprehensive reply. Therefore, the aim of this study consisted of determining the elemental composition of ready-to-consume ayahuasca samples produced in Brazil, in order to evaluate the safety in the oral administration of this beverage, considering recommended macroelement and microelement daily intake values and the permitted limits of potentially toxic heavy metals. Real ayahuasca samples, obtained from Brazilian religious groups, underwent microwave radiation-assisted acid decomposition, and Li, Al, Mn, Fe, Co, Cu, Zn, As, Cd, Hg, and Pb concentrations were determined by ICP-MS, while Ca, Mg, K, and P concentrations were determined by ICP OES. Method accuracy was assessed by analyte addition and recovery assays. Recoveries ranged from 80 and 118%, indicating satisfactory accuracy. Limit of detection (LOD) and limit of quantification (LOQ) values were lower than 1 mg L⁻¹ for the macroelements determined by ICP OES and lower than 3.5 μg L⁻¹ for the microelements determined by ICP-MS. The concentrations of the elements determined in the samples were lower than the recommended or tolerable limits; hence, it is possible to affirm that ayahuasca presents safe administration levels regarding total elemental content.

在过去的几十年中，世界上以阿亚瓦斯卡为原料的啤酒的消费量有所增长，而阿亚瓦斯卡是由两家亚马逊工厂的水煎制而成的。这一事实引起了人们对其口服安全性的质疑。从这个意义上讲，有关鱼化学成分的信息对于找到全面的答复至关重要。因此，这项研究的目的是确定巴西生产的即食阿育吠陀样品的元素组成，以评估口服这种饮料的安全性，并考虑建议的大元素和微量元素的每日摄入量以及允许的摄入量。潜在毒性重金属的限量。来自巴西宗教团体的真实阿育吠陀样品经过微波辐射辅助酸分解，以及Li，Al，Mn，Fe，Co，Cu，Zn，As，Cd，Hg，ICP-MS测定铅和铅的浓度，ICP OES测定钙，镁，钾和磷的浓度。通过分析物添加和回收分析评估方法的准确性。回收率介于80％和118％之间，表明准确性令人满意。检出限（LOD）和定量限（LOQ）值均低于1 mg L^-1用于确定常量元素通过ICP OES和低于3.5微克大号^-1的微量元素测定通过ICP-MS。样品中测定的元素浓度低于建议的或可忍受的限值；因此，有可能确认ayahuasca在总元素含量方面显示出安全的管理水平。