Background: It is well-established that heart failure has a negative impact on quality of life. However, little is known about patient-related predictors of health-related quality of life, anxiety and depression, symptoms and illness perception among patients with heart failure. Aim: To study the association between patient-related predictors and patient-reported outcome measures at discharge from hospital in a cohort of patients with heart failure. Methods: We used data from 1506 patients with heart failure, participating in the national DenHeart Survey of patient-reported outcome measures in patients with heart disease. The potential patient-related predictors included demographic, administrative, clinical and socioeconomic factors. The patient-reported outcome measures included six questionnaires: the Short Form-12, the Hospital Anxiety and Depression Scale, the EuroQol five-dimensional, five-level questionnaire, the HeartQoL, the Brief Illness Perception Questionnaire and the Edmonton Symptom Assessment Scale. Data were linked to national patient registry data and medical records. We performed multivariable linear and logistic regression analyses. Results: In adjusted linear regression analyses we found that a length of hospital stay of >2 days was associated with worse scores across questionnaires, except for the Brief Illness Perception Questionnaire. Higher comorbidity level was associated with worse scores across all questionnaires, whereas low social support was associated with worse scores across questionnaires, except for the physical domain of the Short Form-12 and the HeartQoL global score. Conclusions: This study identified length of hospital stay > 2 days, a higher comorbidity level and low social support to be associated with worse scores across questionnaires at discharge from a cardiac-related hospitalisation in patients with heart failure.

中文翻译：

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心力衰竭患者出院时患者报告结局的预测因素

背景：众所周知，心力衰竭对生活质量有负面影响。然而，对于心力衰竭患者与健康相关的生活质量、焦虑和抑郁、症状和疾病感知的患者相关预测因子知之甚少。目的：研究一组心力衰竭患者出院时与患者相关的预测因子与患者报告的结果测量之间的关联。方法：我们使用了来自 1506 名心力衰竭患者的数据，这些患者参与了国家 DenHeart 调查，对心脏病患者报告的结果测量进行了调查。潜在的与患者相关的预测因素包括人口统计学、行政管理、临床和社会经济因素。患者报告的结果测量包括六份问卷：Short Form-12，医院焦虑和抑郁量表、EuroQol 五维五级问卷、HeartQoL、短暂疾病感知问卷和埃德蒙顿症状评估量表。数据与国家患者登记数据和医疗记录相关联。我们进行了多变量线性和逻辑回归分析。结果：在调整后的线性回归分析中，我们发现住院时间超过 2 天与问卷中得分较差有关，除了简短的疾病感知问卷。较高的合并症水平与所有问卷中的较差分数相关，而低社会支持与问卷中的较差分数相关，除了 Short Form-12 的物理领域和 HeartQoL 整体评分。结论：