Background: Despite the potential foetal and maternal risks of self-medication, studies on self-medication and safety profile of medicines used during pregnancy are scarce. This study determined the prevalence, predictors and safety profile of medicines used for self-medication during pregnancy at Jimma University Medical Centre (JUMC) in Ethiopia. Methods: A hospital-based cross sectional study was conducted on 1117 hospitalized pregnant women or postpartum women in the maternity and gynaecology wards at JUMC between February and June 2017. Data were collected using an interviewer-administered structured questionnaire and by reviewing patient medical records. Data were analysed using descriptive statistics and logistic regression. Result: Nearly 3 out of 10 women reported taking at least one type of conventional medicine for self-medication, mainly analgesics 92.3%. Almost 75.0% of the self-medicated women used medicines classified as probably safe and 13.6% as potentially risky to use during pregnancy. Medicinal plant use, religion and access to a health facility near their residency were significantly associated with self-medication during pregnancy. Conclusions: Self-medication is common among pregnant women at JUMC. Most women used medicines classified as safe to use during pregnancy. There is need for enlightenment of pregnant women on the potential dangers of self-medication during pregnancy to prevent foetal and maternal risks.

中文翻译：

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埃塞俄比亚吉马三级教学医院孕妇使用药物的自我用药和安全性概况：一项跨领域研究。

背景：尽管可能存在胎儿和母亲自我用药的风险，但关于妊娠期间使用药物的自我用药和安全性的研究却很少。这项研究确定了埃塞俄比亚吉马大学医学中心（JUMC）怀孕期间自我用药的普遍性，预测因素和安全性。方法：2017年2月至2017年6月间，在JUMC的妇产科病房中对1117名住院孕妇或产后妇女进行了医院横断面研究。使用描述性统计和逻辑回归分析数据。结果：十分之三的妇女报告至少服用一种传统的自我药物疗法，主要是止痛药92.3％。大约75.0％的自用药妇女在怀孕期间使用了可能安全的药物，并有13.6％的使用风险。在怀孕期间，药用植物的使用，宗教信仰以及在其居住地附近获得医疗设施的使用与自我药物治疗密切相关。结论：JUMC孕妇中自我用药很普遍。大多数妇女在怀孕期间使用被归类为安全使用的药物。有必要对孕妇进行启发，提醒他们在怀孕期间自我用药的潜在危险，以预防胎儿和产妇的风险。宗教信仰和在居住地附近使用保健设施与怀孕期间的自我服药密切相关。结论：JUMC孕妇中自我用药很普遍。大多数妇女在怀孕期间使用被归类为安全使用的药物。有必要对孕妇进行启发，提醒她们在怀孕期间自我用药的潜在危险，以预防胎儿和产妇的风险。宗教信仰和在居住地附近使用医疗设施与怀孕期间的自我服药密切相关。结论：JUMC孕妇中自我用药很普遍。大多数妇女在怀孕期间使用被归类为安全使用的药物。有必要对孕妇进行启发，提醒她们在怀孕期间自我用药的潜在危险，以预防胎儿和产妇的风险。