Meal ingestion triggers secretion of a variety of gut and endocrine peptides important in diabetes research which are routinely measured by immunoassays. However, similarities between some peptides (glucagon, oxyntomodulin and glicentin) can cause specificity issues with immunoassays. We used an LC/MS/MS methodology for unambiguously monitoring multiple gut peptides in human plasma.

中文翻译：

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对照和胃切除患者口服葡萄糖后循环肽组的质谱表征。

膳食摄入会触发多种肠道和内分泌肽的分泌，这些肽在糖尿病研究中很重要，这些肽通常通过免疫测定法进行测量。然而，某些肽（胰高血糖素、胃泌酸调节素和 glicentin）之间的相似性可能会导致免疫测定的特异性问题。我们使用 LC/MS/MS 方法明确监测人血浆中的多种肠肽。