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Recent advances in development of biosensors for taste-related analyses
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2020-06-04 , DOI: 10.1016/j.trac.2020.115925
Ninglong Zhang , Xuan Wei , Yuxia Fan , Xirui Zhou , Yuan Liu

With the continuous research breakthroughs on the gustatory system, special biosensors have been developed for taste-related analyses, such as taste perception, transduction, signaling pathways, and taste detection. Taste biosensors provide high sensitivity and specificity for taste analysis, which can achieve real-time and efficient acquisition of taste information in the target object. Moreover, partial-taste biosensors have been integrated based on mimic or natural taste components of mammals (e.g. taste epithelium, taste cells, taste receptors or whole animals). Thus, they have become a main research component of gustatory system correlations. At present, taste biosensors are still under development, the limitation of their application mainly caused by long-term storage/performance stability, high cost, and low production yield. Overcoming these shortcomings will drive the research for practical application of taste biosensors. The review aims to show the great potential of taste biosensors for gustatory system-related analysis and taste detection, and to provide an update on advances in taste-based biosensors. In addition, the challenges and future perspectives of these devices in performance improvement, development and application are discussed.



中文翻译:

用于味觉相关分析的生物传感器的最新进展

随着味觉系统的不断研究突破,已经开发出用于与味觉相关的分析的特殊生物传感器,例如味觉,转导,信号传导途径和味觉检测。味觉生物传感器为味觉分析提供了高灵敏度和特异性,可以实现目标对象中味觉信息的实时,高效获取。此外,已经基于哺乳动物的模拟或自然味觉成分(例如,味觉上皮,味觉细胞,味觉受体或整个动物)整合了部分味觉生物传感器。因此,它们已成为味觉系统相关性的主要研究组成部分。目前,味觉生物传感器仍在开发中,其应用的局限性主要是由于长期存储/性能稳定性,成本高和产量低引起的。克服这些缺点将推动味觉生物传感器的实际应用研究。这篇综述旨在展示味觉生物传感器在与味觉系统相关的分析和味觉检测方面的巨大潜力,并提供基于味觉的生物传感器的最新进展。此外,还讨论了这些设备在性能改善,开发和应用中的挑战和未来前景。

更新日期:2020-07-06
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