Background and Purpose:Because of several methodological limitations, previous studies focusing on the prevalence of large vessel occlusion in ischemic stroke (IS) patients provided conflicting results. We evaluated the incidence of IS with a visible arterial occlusion using a comprehensive population-based registry.Methods:Patients with acute IS were prospectively identified among residents of Dijon, France, using a population-based registry (2013–2017). All arterial imaging exams were reviewed to assess arterial occlusion. Annual incidence rates of IS (first-ever and recurrent events) and IS with a visible occlusion were calculated.Results:One thousand sixty cases of IS were recorded (mean age: 76.0±15.8 years, 53.9% women). Information about arterial imaging was available in 971 (91.6%) of them, and only preexisting dementia was independently associated with having missing information (odds ratio=0.34 [95% CI, 0.18–0.65], P=0.001). Among these patients, 284 (29.2%) had a visible arterial occlusion. Occlusion site was the anterior circulation in 226 patients (23.3% of overall patients with available data) and the posterior circulation in 58 patients (6.0%). A proximal occlusion of the anterior circulation was observed in 167 patients (17.2%). The crude annual incidence rate of total IS per 100 000 was 138 (95% CI, 129–146). Corresponding standardized rates were 66 (95% CI, 50–82) to the World Health Organization and 141 (95% CI, 118–164) to the 2013 European populations. The crude annual incidence rate of IS with a visible arterial occlusion per 100 000 was 37 (95% CI, 33–41) and that of IS with a proximal occlusion of the anterior circulation was 22 (95% CI, 18–25). Corresponding standardized rates were 18 (95% CI, 10–26) and 10 (95% CI, 8–13) to the World Health Organization population, and 38 (95% CI, 26–50) and 23 (95% CI, 19–26) to the 2013 European population, respectively.Conclusions:These results will be helpful to plan the need for thrombectomy-capable stroke center resources.

中文翻译：

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可见动脉闭塞的急性缺血性中风的发病率：一项基于人群的研究（第戎中风病登记处）。

背景与目的：由于一些方法学上的局限性，以往针对缺血性卒中（IS）患者大血管闭塞的患病率的研究提供了相互矛盾的结果。我们使用基于人群的综合注册表评估了可见动脉闭塞的IS发生率。方法：采用基于人群的注册表（2013-2017年）在法国第戎居民中前瞻性鉴定患有急性IS的患者。所有的动脉成像检查均经过评估，以评估动脉闭塞情况。结果：记录了160例IS病例（平均年龄：76.0±15.8岁，女性为53.9％）。其中971个（91.6％）可获得有关动脉成像的信息，P= 0.001）。在这些患者中，有284位（29.2％）患有可见的动脉闭塞。阻塞部位为226例患者的前循环（占现有数据的23.3％）和58例患者的后循环（6.0％）。在167例患者中观察到前循环的近端闭塞（17.2％）。每10万总IS的粗略年发生率为138（95％CI，129–146）。对应的标准化比率是：世界卫生组织为66（95％CI，50-82），2013年欧洲人口为141（95％CI，118-164）。每10万人具有可见动脉闭塞的IS的粗略年发生率是37（95％CI，33–41），前循环近端闭塞的IS的年发生率是22（95％CI，18–25）。相应的标准化率分别为18（95％CI，10-26）和10（95％CI，