Current Perspective of Antiviral Strategies against COVID-19.,ACS Infectious Diseases

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Current Perspective of Antiviral Strategies against COVID-19.
ACS Infectious Diseases ( IF 4.0 ) Pub Date : 2020-06-02 , DOI: 10.1021/acsinfecdis.0c00236
Bintou A Ahidjo _{1,

2,

3} , Marcus Wing Choy Loe _{2,

3} , Yan Ling Ng _{2,

3} , Chee Keng Mok _{1,

2,

3} , Justin Jang Hann Chu _{1,

2,

3,

4}

Affiliation

COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. This novel coronavirus disease, caused by the SARS-CoV-2 virus, has resulted in severe and unprecedented social and economic disruptions globally. Since the discovery of COVID-19 in December 2019, numerous antivirals have been tested for efficacy against SARS-CoV-2 in vitro and also clinically to treat this disease. This review article discusses the main antiviral strategies currently employed and summarizes reported in vitro and in vivo efficacies of key antiviral compounds in use.

中文翻译：

针对 COVID-19 的抗病毒策略的当前观点。

世界卫生组织于 2020 年 3 月 11 日宣布 COVID-19 为大流行病。这种由 SARS-CoV-2 病毒引起的新型冠状病毒疾病在全球范围内造成了严重且前所未有的社会和经济混乱。自 2019 年 12 月发现 COVID-19 以来，已经测试了多种抗病毒药物对 SARS-CoV-2 的体外疗效以及临床治疗这种疾病的效果。这篇综述文章讨论了目前采用的主要抗病毒策略，并总结了所报道的关键抗病毒化合物的体外和体内功效。

更新日期：2020-07-10

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