ABSTRACT

Inflammation plays a major role in etiology of multiple diseases and it has become an imperative therapeutic target in pharmacological interventions. Over the years, natural products originating from plants have made great contributions in the drug discovery process. Belonging to the Asteraceae family, Stevia rebaudiana (S. rebaudiana) is exploited at a large scale for its purpose as a natural sweetener. Even so, researchers have begun to notice other bioactive potential use of stevia such as anti-inflammatory and anti-cancer activities, which are conferred by compounds present in the leaves including stevioside, rebaudioside and isosteviol. In this review, we provide a brief overview of S. rebaudiana plant and its bioactive compounds and highlight their anti-inflammatory potential for therapeutic applications.

摘要

炎症在多种疾病的病因中起着主要作用，并且已成为药理学干预中的当务之急。多年来，源自植物的天然产物在药物发现过程中做出了巨大贡献。甜菊属（S. rebaudiana）属于菊科（S. rebaudiana），被广泛用作天然甜味剂。即便如此，研究人员已经开始注意到甜叶菊的其他生物活性潜在用途，例如抗炎和抗癌活性，这些作用是由叶中存在的化合物（包括甜菊糖苷，莱鲍迪苷和异osteviol）赋予的。在本文中，我们对S进行了简要概述。Rebaudiana 植物及其生物活性化合物，并突出其在治疗应用中的抗炎潜力。