Lactate accumulation in the brain is caused by the anaerobic metabolism induced by ischemic damages, which always accompanies intracerebral hemorrhages (ICH). Our former findings showed that microglia's movement was always directly toward hemorrhagic center with the highest lactate concentration, and penumbra area has the largest density of compactly arrayed microglia. However, the relationship between microglia and lactate concentration has not been well documented.

中文翻译：

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用 MRI/MRS 和体外方法评估脑出血大鼠脑中乳酸的功能。

大脑中的乳酸积累是由缺血性损伤引起的无氧代谢引起的，缺血性损伤总是伴随着脑出血 (ICH)。我们以前的研究结果表明，小胶质细胞的运动总是直接向乳酸浓度最高的出血中心移动，而半影区的密集排列的小胶质细胞密度最大。然而，小胶质细胞和乳酸浓度之间的关系尚未得到充分证明。