Effective cleaning techniques are essential for the sterilization of rooms in hospitals and industry. No‐touch devices (NTDs) that use fumigants such as hydrogen peroxide (H₂O₂), formaldehyde (HCHO), ozone (O₃), and chlorine dioxide (OClO) are a recent innovation. This paper reports a previously unconsidered potential consequence of such cleaning technologies: the photochemical formation of high concentrations of hydroxyl radicals (OH), hydroperoxy radicals (HO₂), organic peroxy radicals (RO₂), and chlorine radicals (Cl) which can form harmful reaction products when exposed to chemicals commonly found in indoor air. This risk was evaluated by calculating radical production rates and concentrations based on measured indoor photon fluxes and typical fumigant concentrations during and after cleaning events. Sunlight and fluorescent tubes without covers initiated photolysis of all fumigants, and plastic‐covered fluorescent tubes initiated photolysis of only some fumigants. Radical formation was often dominated by photolysis of fumigants during and after decontamination processes. Radical concentrations were predicted to be orders of magnitude greater than background levels during and immediately following cleaning events with each fumigant under one or more illumination condition. Maximum predicted radical concentrations (1.3 × 10⁷ molecule cm⁻³ OH, 2.4 ppb HO₂, 6.8 ppb RO₂ and 2.2 × 10⁸ molecule cm⁻³ Cl) were much higher than baseline concentrations. Maximum OH concentrations occurred with O₃ photolysis, HO₂ with HCHO photolysis, and RO₂ and Cl with OClO photolysis. Elevated concentrations may persist for hours after NTD use, depending on the air change rate and air composition. Products from reactions involving radicals could significantly decrease air quality when disinfectants are used, leading to adverse health effects for occupants.

中文翻译：

---

医院病房清洁后，光解驱动的室内空气化学反应。

有效的清洁技术对于医院和行业中的房间灭菌至关重要。使用熏蒸剂（例如过氧化氢（H ₂ O ₂），甲醛（HCHO），臭氧（O ₃）和二氧化氯（OClO））的非接触式设备（NTD）是一项最新的创新。本文报告了这种清洁技术以前未曾考虑过的潜在后果：高浓度羟自由基（OH），氢过氧自由基（HO ₂），有机过氧自由基（RO ₂）的光化学形成）和氯自由基（Cl），当暴露于室内空气中常见的化学物质时会形成有害的反应产物。通过在清洁过程中和清洁后测量的室内光子通量和典型的熏蒸剂浓度，通过计算自由基的产生速率和浓度来评估这种风险。无盖的阳光和荧光灯管引发了所有熏蒸剂的光解，塑料覆盖的荧光灯管引发了仅一些熏蒸剂的光解。在净化过程中和净化过程之后，熏蒸剂的光解作用通常会导致自由基形成。预计在每种熏蒸剂在一种或多种光照条件下进行清洁期间和之后，其自由基浓度将比背景水平高几个数量级。最大预测自由基浓度（1.3×10⁷分子厘米^-3 OH，2.4 ppb的HO ₂，6.8 ppb的RO ₂和2.2×10 ⁸分子厘米^-3 Cl）的比基线浓度高得多。O ₃光解发生最大的OH浓度，HCHO光解发生HO _2的最大浓度，OClO光解产生RO ₂和Cl的最大浓度。NTD使用后，浓度升高可能会持续数小时，具体取决于空气变化率和空气成分。使用消毒剂时，涉及自由基的反应产生的产品可能会大大降低空气质量，从而对乘员的健康产生不利影响。