Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE
ChemistryOpen
(
IF2.5
)
Pub Date : 2020-06-02, DOI: 10.1002/open.202000132
Anton Zalygin
1
,
Daria Solovyeva
1
,
Ivan Vaskan
1,
2
,
Stephen Henry
3
,
Marcel Schaefer
3
,
Pavel Volynsky
1
,
Alexander Tuzikov
1
,
Elena Korchagina
1
,
Ivan Ryzhov
1
,
Alexey Nizovtsev
1
,
Konstantin Mochalov
1
,
Roman Efremov
1,
4
,
Eleonora Shtykova
5,
6
,
Vladimir Oleinikov
1,
2
,
Nicolai Bovin
1
Affiliation
Shemyakin-Ovchinnikov Institute of Bioorganic ChemistryRussian Academy of Sciences 16/10 Miklukho-Maklaya str. Moscow 117997 Russia
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) Kashirskoe shosse 31 Moscow 115409 Russian Federation
School of EngineeringComputer & Mathematical SciencesAuckland University of Technology Auckland 1010 New Zealand
National Research University Higher School of Economics Myasnitskaya Str. 20 Moscow 101000 Russian Federation
Shubnikov Institute of Crystallography of Federal Scientific Research Centre 'Crystallography and Photonics' of Russian Academy of Sciences Moscow 119333 Russian Federation
Semenov Institute of Chemical PhysicsRussian Academy of Sciences Moscow 119991 Russian Federation
The Front Cover shows how a biotin residue initially hidden in a monolayer formed on the surface of a material by biot‐CMG‐DOPE is pulled out of the layer by the streptavidin molecule that has come close to it. This can be considered as a model for the surface of a living cell: sometimes molecules are able to hide from undesirable interactions and yet leave the possibility to be recognized by high‐affinity proteins. The picture is inspired by the legendary Yellow Submarine cartoon. More information can be found in the Full Paper by Anton Zalygin al.
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