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Technique for simple apatite coating on a dental resin composite with light-curing through a micro-rough apatite layer.
Biomaterials Advances ( IF 5.5 ) Pub Date : 2020-06-03 , DOI: 10.1016/j.msec.2020.111146
Yasushi Hibino 1 , Ayako Oyane 2 , Kanako Shitomi 3 , Hirofumi Miyaji 3
Affiliation  

Tooth root surfaces restored with dental resin composites exhibit inferior biocompatibility. The objective of this study was to develop a simple technique for coating apatite onto a resin composite to improve its surface biocompatibility. First, we fabricated a polymer film coated with a micro-rough apatite layer and pressed it (coating-side down) onto a viscous resin composite precursor. As a result of light-induced curing of the precursor through the overlaid film, the micro-rough apatite layer was integrated with the resin composite and, thus, transferred from the polymer film surface to the cured resin composite surface as a result of the difference in interfacial adhesion strength. The transferred apatite layer attached directly to the cured resin composite without any gaps at the microscopic level. The adhesion between the apatite layer and the cured resin composite was so strong that the layer was not peeled off even by a tape-detaching test. The flexural strength of the resulting apatite-coated resin composite was comparable to that of the clinically used resin composite while satisfying the ISO requirement for dental polymer-based restorative materials. Furthermore, the apatite-coated resin composite showed better cell compatibility than the uncoated resin composite. The present apatite coating technique is well suited for dental treatment because the coating is applied during a conventional light curing procedure through simple utilization of the apatite-coated polymer film in place of an uncoated film. The proposed technique represents a practical evolution in dental treatment using light-curing resin composites, although further in vitro and in vivo studies are needed.



中文翻译:

通过微粗糙磷灰石层进行光固化,从而在牙科树脂复合材料上进行简单磷灰石涂层的技术。

用牙科树脂复合材料修复的牙根表面生物相容性较差。这项研究的目的是开发一种将磷灰石涂覆到树脂复合材料上以改善其表面生物相容性的简单技术。首先,我们制造了一个涂有微粗糙磷灰石层的聚合物膜,并将其压在(涂层面朝下)到粘性树脂复合材料前体上。通过覆盖膜对前驱物进行光诱导固化的结果,微粗糙磷灰石层与树脂复合材料成为一体,并由于这种差异而从聚合物膜表面转移至固化的树脂复合材料表面界面粘合强度。转移的磷灰石层直接附着在固化的树脂复合材料上,在微观水平上没有任何间隙。磷灰石层与固化的树脂复合物之间的粘附力是如此强,以至于即使通过胶带剥离试验也不会剥离该层。所得磷灰石涂层树脂复合材料的弯曲强度与临床上使用的树脂复合材料相当,同时满足了牙科聚合物基修复材料的ISO要求。此外,磷灰石涂覆的树脂复合材料显示出比未涂覆的树脂复合材料更好的电池相容性。本发明的磷灰石涂层技术非常适合于牙科治疗,因为在常规的光固化过程中通过简单地利用磷灰石涂层的聚合物膜代替未涂层的膜来施加涂层。所提出的技术代表了在使用光固化树脂复合材料的牙科治疗中的实际发展,尽管进一步 所得磷灰石涂层树脂复合材料的弯曲强度与临床上使用的树脂复合材料相当,同时满足了牙科聚合物基修复材料的ISO要求。此外,磷灰石涂覆的树脂复合材料显示出比未涂覆的树脂复合材料更好的电池相容性。本发明的磷灰石涂层技术非常适合于牙科治疗,因为在常规的光固化过程中通过简单地利用磷灰石涂层的聚合物膜代替未涂层的膜来施加涂层。所提出的技术代表了使用光固化树脂复合材料在牙科治疗中的实际发展,尽管进一步 所得磷灰石涂层树脂复合材料的弯曲强度与临床上使用的树脂复合材料相当,同时满足了牙科聚合物基修复材料的ISO要求。此外,磷灰石涂覆的树脂复合材料显示出比未涂覆的树脂复合材料更好的电池相容性。本发明的磷灰石涂层技术非常适合于牙科治疗,因为在常规的光固化过程中通过简单地利用磷灰石涂层的聚合物膜代替未涂层的膜来施加涂层。所提出的技术代表了在使用光固化树脂复合材料的牙科治疗中的实际发展,尽管进一步 本发明的磷灰石涂层技术非常适合于牙科治疗,因为在常规的光固化过程中通过简单地利用磷灰石涂层的聚合物膜代替未涂层的膜来涂覆涂层。所提出的技术代表了在使用光固化树脂复合材料的牙科治疗中的实际发展,尽管进一步 本发明的磷灰石涂层技术非常适合于牙科治疗,因为在常规的光固化过程中通过简单地利用磷灰石涂层的聚合物膜代替未涂层的膜来施加涂层。所提出的技术代表了在使用光固化树脂复合材料的牙科治疗中的实际发展,尽管进一步需要进行体外体内研究。

更新日期:2020-06-03
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