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Dosimetric evaluation of phantoms including metal objects with high atomic number for use in intensity modulated radiation therapy.
Radiation and Environmental Biophysics ( IF 1.7 ) Pub Date : 2020-06-01 , DOI: 10.1007/s00411-020-00851-0
Aysun Inal 1 , Ismail Hakki Sarpün 2, 3
Affiliation  

The dosimetric effect of artefacts caused by metal hip prostheses in computed tomography imaging is most commonly encountered in the planning of prostate cancer treatment. In this study, a phantom, containing a metal with high atomic number, was prepared for intensity-modulated radiotherapy (IMRT) treatment plans to be used in quality assurance (QA) procedures. Two sets of image files, one without metal artefact correction (ORG) and another with MAR correction (MAR+), were sent to the treatment planning system. In this study, 12 IMRT treatment plans with different fields and segment numbers were calculated. The normal tissue complication probability (NTCP) values of imaginary organs at risk (OARs), such as the rectum and bladder, were investigated, as was the difference in dose maps for ORG and MAR+ derived by calculating gamma passing rates (GPRs). The MatriXX was used for the gamma evaluation of patient-specific IMRT QA measurements. The gamma evaluation was repeated, based on the measurements using an EBT3 gafchromic film, for the plan showing the lowest GPR. The mean relative difference in NTCP values between the two sets of image files was found to be 2.5, 2.1 and 1.4 for the rectum; and 5.33, 6.80 and 9.82 for the bladder, for the investigated 5-, 7- and 9-field beam arrangements, respectively. The relative differences and the standard deviations in GPRs for the standard and metal-containing phantoms were calculated for the MAR+ and ORG sets. The maximum difference found was 7.69% ± 0.88 for the 9-field beam arrangement calculated without metal artefact correction. In the IMRT QA procedures for prostate patients with hip prostheses, the application of a metal-containing phantom that is both easy and inexpensive to prepare, is considered to be a useful method for examining any dose changes involved in introducing a hip prosthesis. Therefore, it is recommended for use in clinics that do not have MAR correction algorithms.



中文翻译:

幻影的剂量学评估,包括具有高原子序数的金属物体,用于强度调制放射治疗。

在计划性的X射线断层摄影术中,由金属髋关节假体引起的伪影的剂量效应最常在前列腺癌治疗的规划中遇到。在这项研究中,准备了一种包含高原子序数的金属的体模用于强度调制放射疗法(IMRT)治疗计划,以用于质量保证(QA)程序。将两套图像文件发送到治疗计划系统,其中一套没有金属伪影校正(ORG),另一套没有MAR校正(MAR +)。在这项研究中,计算出了12种不同领域和段号的IMRT治疗计划。研究了处于危险状态的虚构器官(OAR)(例如直肠和膀胱)的正常组织并发症发生率(NTCP)值,通过计算伽玛通过率(GPR)得出的ORG和MAR +剂量图的差异也是如此。MatriXX用于对患者特定的IMRT QA测量值进行伽马评估。根据使用EBT的测量结果,重复进行γ评估3全反射膜,用于显示最低GPR的计划。两组图像文件之间的NTCP值的平均相对差异被发现是直肠的2.5、2.1和1.4。对于研究的5场,7场和9场射束布置,分别为5.33、6.80和9.82(膀胱)。对于MAR +和ORG集,计算了标准模型和含金属模型的GPR的相对差异和标准偏差。对于未经金属伪影校正而计算出的9场光束布置,发现的最大差异为7.69%±0.88。在针对具有髋关节假体的前列腺患者的IMRT QA程序中,使用易于制备且廉价的含金属体模的应用被认为是检查与引入髋关节假体有关的任何剂量变化的有用方法。因此,

更新日期:2020-06-01
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